Yes — self-employed individuals can deduct 100% of health, dental, and vision insurance premiums paid for themselves, their spouse, and dependents as an above-the-line deduction on Form 1040. You don't need to itemize to take this deduction. The deduction reduces your AGI but does not reduce your self-employment tax base. You cannot take this deduction for any month in which you were eligible to enroll in a subsidized employer plan through a spouse. The deduction also applies to Medicare premiums if you're self-employed and age 65 or older.