Most businesses rely on software, and those subscription costs are among the most straightforward deductions available. Software subscriptions used in your business, such as accounting software, project management tools, design programs, or customer relationship management systems, are fully deductible as business expenses. If you use software for both personal and business purposes, only the business portion is deductible. Annual or monthly subscription fees are deducted in the period they are paid for most small businesses. Employees who pay for their own software tools without reimbursement generally cannot deduct those costs under current law.